Active Government Funding Opportunities

GLP-compliant preclinical toxicology and pharmacokinetic studies for peptide-displaying liposomal dexamethasone delivery system targeting rheumatoid arthritis, supporting FDA Pre-IND advancement.

Development and maintenance of Terminal Instrument Procedures (TERPS) production software for aeronautical navigation automation. NGA seeks commercial provider for safety-critical navigation data systems.

One-year contract extension with Southwest Research Institute for Magnetospheric MultiScale (MMS) mission operations and science data management. Sole-source continuation of established space science operations.

Request for Information on Digital GI Bill platform modernization, cloud migration, and claims processing automation. VA seeks industry input on technical strategies for veterans benefits system transformation.

VA seeks vendors for custom liposomal formulation with patented joint-targeting peptides for rheumatoid arthritis drug delivery, including nanoparticle characterization and formulation validation.

AFRL open BAA for novel aerospace concepts and R&D to mature transformative technologies across TRL levels, enabling study efforts and advanced technology development for warfighter advantage.

Develop innovative detection, characterization, and protective technologies to counter evolving chemical and biological threats across defense, homeland security, and public health sectors. Finalists present solutions at the Defense TechConnect Innovation Summit for potential commercialization partnerships.

Electric grid innovators can access testing and validation services through vouchers worth $50k-$250k to advance pre-commercial transmission and distribution technologies. This support helps startups and entrepreneurs de-risk their innovations before commercialization.

Transmission providers can access expert consulting and training to model advanced grid technologies—like dynamic line ratings and AI-powered studies—that reduce interconnection costs and unlock existing capacity for new loads and generation.

DOE grants help States and local governments adopt building codes that improve affordability, energy efficiency, and resilience. Technical assistance supports jurisdictions in leveraging buildings to meet broader climate and grid stability goals.

States and universities can secure funding to help small manufacturers adopt smart manufacturing technologies and high-performance computing. The program supports workforce training, technical assistance, and direct technology implementation to boost competitiveness.

USDA ARS requests mRNA-sequencing and methyl-bisulfite sequencing analysis services for plant tissue samples in agricultural research.

Market research for cost modeling and financial management software to categorize, track, and report $9B annual IT spending across VA's Budget Structure and calculate Total Cost of Ownership for IT products and services.

Air Force Research Laboratory market research for novel thermal and power management architectures enabling integrated enthalpy management, power generation, and thermal systems for reusable hypersonic aircraft.

NGA seeks continuation of Global Services Proxy (GSP) III system for GEOINT dissemination and international partner connectivity, serving as cross-domain network boundary infrastructure.

DHS S&T seeks comments on Basic Ordering Agreements for Phase XI Centers of Excellence research spanning emerging disease, explosives threats, borders, trade, and coastal resilience.

Navy PAE(A) seeks industry concepts for next-generation unmanned carrier-based aircraft with autonomous capabilities, integrating with MQ-25A and CCA for Naval Aviation Enterprise.

Department of Energy solicitation for solid state amplifier procurement. Limited details available; full documentation accessible through SAM.gov contacts.

AFGSC seeks a reusable, rocket-powered VTOL aircraft prototype that transitions to horizontal flight, integrating autonomous controls, advanced propulsion, and cryogenic systems. This addresses the Air Force's need to mature critical technologies for future long-range strike and responsive operational capabilities.

ERDC's patented CyanoSTUN™ technology uses UV-C light to rapidly eliminate harmful algal blooms in freshwater reservoirs without toxic chemicals. This webinar explores licensing and commercialization opportunities for companies seeking to scale an innovative, field-tested solution addressing a critical water quality challenge.

VA seeks discovery and disclosure platform for unified information management. Request for Information to identify potential technology solutions for healthcare data integration.

DoD TReX II OTA for Training Risk Assurance, Compliance, and Evaluation (TRACE) system prototype development. Innovation solicitation for military readiness modeling and simulation platforms.

Procurement of flex hoses and related hose systems for Department of Energy operations.

R&D BAA addressing subsistence logistics in contested environments, focusing on agile procurement, smart packaging with sensors, and autonomous distribution systems for warfighter sustainment.